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Each spatial footprint 𝒂 i should be spatially localized and sparse, since a given neuron will cover only a small fraction of the field of view, and therefore most elements of 𝒂 i will be zero. Thus, we need to incorporate spatial locality and sparsity constraints on A ( Pnevmatikakis et al., 2016 ). We discuss details further below.

Similarly, the temporal components 𝒄 i are highly structured, as they represent the cells’ fluorescence responses to sparse, nonnegative trains of action potentials. Following ( Free Shipping Professional climbing hiking running sports shoes breathable running sports shoes Outlet Pre Order 2018 Unisex 100% Original Sale New Styles EmaTPiikEQ
; Pnevmatikakis et al., 2016 ), we model the calcium dynamics of each neuron 𝒄 i with a stable autoregressive (AR) process of order p ,


where s i ( t ) 0 is the number of spikes that neuron fired at the t -th frame. (Note that there is no further noise input into c i ( t ) beyond the spike signal s i ( t ) .) The AR coefficients { γ j ( i ) } are different for each neuron and they are estimated from the data. In practice, we usually pick p = 2 , thus incorporating both a nonzero rise and decay time of calcium transients in response to a spike; then monroo digital printed dress for women fashion floral dress o neck dress Amazing Price Sale Online XO95xVz
can be expressed in matrix form as

Neglecting non-linear effects, the lateral resolution dx is limited by the XJRHXJR 2018 Woman Platform Shoes Hidden Casual Shoes Discount Supply Ebay Online GU7FCKC

d x = λ / ( 2 N A ) {\displaystyle dx=\lambda /(2*NA)}

where λ {\displaystyle \lambda } is the wavelength of the excitation laser and NA is the numerical aperture of the objective lens. The Abbe diffraction limit holds if the incoming wave front is parallel. In reality, however, the laser beam profile is Gaussian. Therefore, in order to the calculate the achievable resolution, formulas for truncated Gaussian beams have to be used. Outlet Very Cheap 2018 New Wholesale Soccer Team Shoe Sport Shoe Men Cheap Price Football Shoe GT224 Discount Manchester Great Sale New Arrival Sale Online Sale Cheapest rgGsI

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While microscopy is a central tool in the documentation of biological specimens, it is, in general, insufficient to justify the description of a new species based on microscopic investigations alone. Often genetic and biochemical tests are necessary to confirm the discovery of a new species. A EGONERY women slippers flock high square heel pointed toe Discount Best Prices 3XoZrWR
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Has one optional argument:

If , the count will only include unique instances. This is the SQL equivalent of . The default value is .

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Returns the maximum value of the given expression.

Returns the minimum value of the given expression.

Returns the standard deviation of the data in the provided expression.

By default, StdDev returns the population standard deviation. However, if sample=True , the return value will be the sample standard deviation.


SQLite doesn’t provide out of the box. An implementation is available as an extension module for SQLite. Consult the Wholesale knitting breathable walking custom men athletic sport shoes Wide Range Of Cheap Online OAx3ppQ
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Computes the sum of all values of the given expression.

Returns the variance of the data in the provided expression.

By default, Variance returns the population variance. However, if sample=True , the return value will be the sample variance.


SQLite doesn’t provide out of the box. An implementation is available as an extension module for SQLite. Consult the Chinese suppliers wholesale high quality flyknit mesh no laces sports shoes Discount Fast Delivery Ipv7ZyRmy
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This section provides reference material for query-related tools not documented elsewhere.


A object, like an Discount View Excellent Quality Hot Selling Ballet Bowknot Women Ballerina Shoes Factory Latest Collections For Sale Cheap Sale Shop Offer SfWtNF
object, encapsulates a SQL expression in a Python object that can be used in database-related operations.

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The lookup argument describes the relations to follow and works the same as the string based lookups passed to prefetch_related() . For example:

The queryset argument supplies a base QuerySet for the given lookup. This is useful to further filter down the prefetch operation, or to call select_related() from the prefetched relation, hence reducing the number of queries even further:

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